A couple of points I missed in my first post.
You can try and build the loom in the car but there's just no way you'll get it neat and get that manufactured appearance to it.
Noted the idea of moving away from the standard connectors. Yes, there's much better connectors about these days but you're simply not going to get away from all the old ones, items like Headlights, Tail Lamp assemblies, some of the Front Parkers, Instruments and many other items, no matter what, you are already locked in. Then there's items like the Blinker Switch, yes, you could change that, but then you have something that's not 'off the shelf' replaceable, you'll need to buy your new Switch, change the plug and void the warranty on it in the process then fit it. I'd suggest having a good look over all the items in the car (and those you'd like to move to) and think each item through here.
I've found with old harnesses, the wire itself gives little trouble, it's the old connectors, in particular the multipin plugs that do give trouble. I've also found that when new, all these same connectors, including the bullets, when new give zero trouble and do so for a very long time. I think the modern sealed type of connectors came in to vogue in newer cars as electronics were added to them as a Computer is much more fussy and needs good clean signals, many of which are at a 'low level' than say the 20 or so Amps you need to run your Lucas Headlamps.
I prefer to build looms from scratch too, but as mentioned can be expensive to tool up for and buy cable. My approach is to use single colour cable for the whole loom, 100m reels of single colour are relatively cheap and you only need 3 gauges of cable (plus the odd lengths for the battery and main feeds to the fuse box. I use heat shrink to colour code the ends of the cables.
The first loom I made (and made many errors, but also learnt a LOT from), I did in a similar way, single coloured and marked ends. Fair play if you are happy with them Mike, knock yr socks off
but I gotta say, I found I didn't like it. I found the marked ends easily damaged and after a while, some became hard or impossible to read, not for any of them being some cheap and nasty thing, but the environment they were in, especially in the engine bay. It also meant for me, absolutely everything I needed to refer to my diagrams and notes to see what was what, where as with the colour coded wires I know them by memory and I seldom need to refer to anything (only for wipers) to know what each wire is. Purely as a vanity thing, I also didn't like the appearance of the loom having all the same colours in it, sorry to say it this way, but it looked really 'home made' but I stress,,, that's just purely vanity !!