Just reading Shooter's comments there on the Merc engine, a friend and colleague routinely does a fair bit of the more difficult machining work on 'vintage' F1 engines, a few years back, he had the Hart engine from Allan Jone's Turbo F1 car. That had 450 seats in it, but then it ran cira 45 PSI boost pressure too. To avoid head gasket issues, the head and block were cast one piece (and that's why this particular engine landed in his bench)
I can see where 'flater' valve seat angles can help with lower valve lifts, but then, I think much could be gained from observations and tests on the flow bench. Have you done any plots Phil ?